Rapid DNA test could cut brain tumour diagnosis from weeks to hours

Thousands of NHS patients with suspected brain tumours could receive faster diagnoses through a new pilot of rapid genomic testing across England.

The test analyses the DNA of a small tumour sample collected during a biopsy or operation, helping doctors identify the precise tumour type within days rather than waiting several weeks. This could allow treatment such as chemotherapy or radiotherapy to begin sooner.

In some operations, results can be returned in under two hours while the patient is still in theatre. Surgeons could then use the information to decide how much of the tumour can safely be removed while protecting healthy brain tissue.

Faster genomic results could also help patients enter suitable clinical trials earlier, as eligibility for some studies depends on the genetic characteristics of their tumour.

The technology was developed by scientists and clinicians at the University of Nottingham and Nottingham University Hospitals NHS Trust. Following earlier work in Nottingham and Birmingham, NHS England will initially introduce it at five specialist centres before expanding it further.

Professor Frankie Swords, NHS medical director, described the test as a “huge leap forward” that could transform brain tumour diagnosis and support potentially life-changing decisions during surgery.

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